Associate, Process Sciences - Cambridge, MA

    • Job Tracking ID: 85430-279461
    • Job Location: Cambridge, MA
    • Job Level: Any
    • Level of Education: Any
    • Job Type: Full-Time/Regular
    • Date Updated: 01/08/2019
    • Years of Experience: Not Applicable
    • Starting Date: ASAP
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Job Description

JOB SUMMARY/OBJECTIVE:

The primary responsibility is to support the process establishment and process characterization for the manufacturing of viral vectors. This position requires close interaction with the Process Sciences (PS) colleagues, Manufacturing Science & Technology, Manufacturing, Process Development, and other departments. This role will focus on defining and characterizing robust, scalable and efficient manufacturing processes to produce late-phase human clinical trial and commercial viral vector products.

The MST Associate will work closely with the MST teams to support client projects and with Brammer’s Florida site, PD, Quality, EHS, MST, and Manufacturing to ensure compliance and technology transfer.

ESSENTIAL RESPONSIBILITIES:

  • Supports cross functional technology transfer teams for DS manufacturing of viral vectors. Collaborate with other sites or clients to ensure success of scale up/ process transfer. Includes authoring of upstream or downstream plan documentation and associated PDPRs.
  • Execute PS process establishment and process characterization runs, ensuring documentation is followed and completed real time.
  • Execute cell culture or downstream laboratory work while maintaining good laboratory practice.
  • Maintain an accurate schedule/project plan of assigned PS lab work and deliverables.
  • Support the PS laboratory to operate efficiently. This may include maintenance of inventory; experiment and equipment use scheduling; and maintenance of equipment.
  • Identifying opportunities to improve systems and practices
  • Work with counterparts in Brammer’s Alachua Process Development and Cambridge Manufacturing Sciences & Technology to facilitate project success.

Experience and Skills

KNOWLEDGE, SKILLS and QUALIFICATIONS:

  • Bachelor or advanced degree in Biochemical, Chemical Engineering or a related scientific discipline such as Chemistry or Biology.
  • MST Associate I: B.S. with less than 2 years’ relevant experience
  • MST Associate II: B.S. with 2-3 years’ relevant experience, or Master’s degree.
  • MST Associate III: B.S. with 4+ years’ relevant experience, or Master’s degree with 1-3 years’ experience
  • Strong interpersonal and communications skills; written and oral.
  • Ability to function in a fast-paced dynamic team environment and balance prioritize multiple projects
  • Laboratory experience preferred.
  • Knowledge of cell and gene therapy vector production highly desirable.
  • Ability to be hands-on

PHYSICAL DEMANDS/FACTORS:

While performing the duties of this job, the employee:

  • Ability to function in a rapidly changing environment & handle multiple priorities.
  • Work Hours: Monday through Friday, 8:00 AM to 5:00 PM. Requires overtime to work evenings, weekends or holidays, as required to meet project timelines.
  • Ability to lift up to 25 lbs.

Note: This job description is not all-inclusive. Additional duties may be performed, as assigned. It acts as a guideline and is subject to change over time.